Cell and gene therapy (CGT) supply chain logistics are undergoing rapid evolution in response to growing demand for personalized, patient-specific treatments, with commercialization and regulatory approvals increasing supply chain complexity124.
The global CGT supply chain market was valued at $1.5 billion in 2024 and is projected to reach $4.4 billion by 2034, with an estimated compound annual growth rate (CAGR) of 11.9%2.
Major challenges include managing cold chain logistics, ensuring strict timelines, robust chain-of-identity, and maintaining product viability during transit; advanced IT, automation, digitization, and artificial intelligence are being adopted to address these issues124.
The industry is moving towards fit-for-purpose, patient-adjacent, and regionalized manufacturing models supported by digital logistics platforms for end-to-end traceability and data management14.
White glove delivery models, such as that implemented by Cardinal Health, are redefining standards by providing unified, national delivery networks with high reliability and rapid response for hospitals and patients3.
Risk mitigation is becoming a strategic priority, with increasing adoption of digital tools for predictive analytics and contingency planning to prevent supply disruptions, especially as the market expands globally and cross-border shipments become more common5.
Industry consolidation through mergers and acquisitions continues as companies seek to strengthen supply chain capabilities and offset revenue losses from patent expirations5.
Sources:
1. https://www.cellgenetherapyreview.com/3975-Featured-Articles/617533-2025-cell-and-gene-challenges-Scalability-supply-chain-and-manufacturing/
2. https://www.insightaceanalytic.com/report/cell-and-gene-therapy-supply-chainlogistics-market-size-share--trends-analysis-report-by-application-area-by-type-of-software-solution-by-mode-of-deployment-by-end-user-biobank-cell-therapy-lab-hospital-research-institute-commercial-organization--by-region-and-by-segment-forecasts-2025-2034/1694
3. https://www.phacilitate.com/insights-resources/redefining-white-glove-delivery-cell-gene-therapy
4. https://www.biospace.com/cell-and-gene-therapy-supply-chain-logistics-market-expected-to-grow-at-a-cagr-of-11-41-percent-from-2024-to-2031
5. https://www.cryoport.com/bio-blog-top-10-industry-predictions-for-2025/